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Recombinant Human Interleukin 15 (a. a. 114)

Recombinant Human Interleukin 15 (a. a. 114)

Item no.	DAG354
Manufacturer	Creative Diagnostics
Amount	10 ug
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	>98%pure (SDS-PAGE and HPLC analysis). Endotoxin level is <0.1ng per ug(1EU/ug). Product is 0.2um filtered.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL15,interleukin 15,IL-15,MGC9721,interleukin-15,OTTHUMP00000164616,OTTHUMP00000164617,OTTHUMP00000218093,OTTHUMP00000228804,OTTHUMP00000228805,IL 15,Interleukin15
Available
Manufacturer - Applications	The ED50as determined by the dose-dependent proliferation of murine CTLL-2cells was found to be <0.5ng/ml, corresponding to a specificactivity of >2 x106 units/mg. Each laboratory shoulddetermine an optimum working titer for use in its particular application.Other applications have not been tested but use in such assays should notnecessarily be excluded.
Storage Conditions	Thelyophilized product, though stable at room temperature, is best stored -20°C.After reconstitution, aliquot and store at –20°C. Avoid multiple freeze/thawcycles.
Full name	Interleukin 15
Product Overview	IL-15 isan immunomodulating cytokine that stimulates the proliferation of Tlymphocytes and shares many biological properties with IL-2. IL-15 exerts itsbiological activities primarily on T cells. It is also essential in thedevelopment, survival and activation of NK cells. Recombinant human IL-15which was expressed in E. coli is a 12.9kDa protein consisting of 114 aminoacid residues.
Abbr	IL15 (a.a. 114)
Manufacturer - Format	Purified, Lyophilized. We recommend a quick spin followed by reconstitution in water toa concentration of 0.1-1.0mg/ml. This solution can then be diluted into otheraqueous buffers and stored (up to 1 week) at 2-8C or stored at –20C forfuture use.
Buffer	Lyophilized from10mM Sodium phosphate, pH 8.5
Concentration	Not applicable
Preservative	None
Gene Information - Gene Name	IL15interleukin 15 [ Homo sapiens ]
Gene Information - mRNA Refseq	NM_000585
Gene Information - Protein Refseq	NP_000576
Gene Information - MIM	600554
Gene Information - Pathway	Cytokine-cytokinereceptor interaction, HTLV-I infection, Herpes simplex infection, Intestinalimmune network for IgA production, Jak-STAT signaling pathway, Rheumatoidarthritis
Gene Information - Function	cytokine activity, cytokine receptor binding, protein binding, signal transducer activity
Antigen Description	Interleukin15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15binds to and signals through the IL-2/IL-15 beta chain (CD122) and the commongamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes(and some other cells) following infection by virus(es). This cytokineinduces cell proliferation of natural killer cells, cells of the innateimmune system whose principal role is to kill virally infected cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/18/2025

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