LRP6 Antibody

ArtNr	CSB-PA013102ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Antibodies By Cell Type Obesity Immunohistochemistry ELISA Lipoprotein Receptors & Associated Proteins Lipid & Fatty Acid Transport Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADCAD2 antibody; C030016K15Rik antibody; Cd antibody; FLJ90062 antibody; FLJ90421 antibody; LDL receptor related protein 6 antibody; Low density lipoprotein receptor related protein 6 antibody; Low-density lipoprotein receptor-related protein 6 antibody; LRP-6 antibody; LRP6 antibody; LRP6_HUMAN antibody; OTTHUMP00000238979 antibody; OTTHUMP00000238980 antibody; OTTHUMP00000238982 antibody; STHAG7 antibody
Similar products	LRP6, Low-density lipoprotein receptor-related protein 6 (LRP-6)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	LRP6
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	ADCAD2 antibody; C030016K15Rik antibody; Cd antibody; FLJ90062 antibody; FLJ90421 antibody; LDL receptor related protein 6 antibody; Low density lipoprotein receptor related protein 6 antibody; Low-density lipoprotein receptor-related protein 6 antibody; LRP-6 antibody; LRP6 antibody; LRP6_HUMAN antibody; OTTHUMP00000238979 antibody; OTTHUMP00000238980 antibody; OTTHUMP00000238982 antibody; STHAG7 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Low-density lipoprotein receptor-related protein 6 protein (20-150AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Antigen Species	Human
Antigen	Recombinant Human Low-density lipoprotein receptor-related protein 6 protein (20-150AA)
Clonality	Polyclonal

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Menge: 50 ul

lieferbar

Lieferung vsl. bis 14.08.2025