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LRP6 Antibody

LRP6 Antibody

Item no.	CSB-PA013102ESR2HU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Antibodies By Cell Type Obesity Immunohistochemistry ELISA Lipoprotein Receptors & Associated Proteins Lipid & Fatty Acid Transport Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADCAD2 antibody; C030016K15Rik antibody; Cd antibody; FLJ90062 antibody; FLJ90421 antibody; LDL receptor related protein 6 antibody; Low density lipoprotein receptor related protein 6 antibody; Low-density lipoprotein receptor-related protein 6 antibody; LRP-6 antibody; LRP6 antibody; LRP6_HUMAN antibody; OTTHUMP00000238979 antibody; OTTHUMP00000238980 antibody; OTTHUMP00000238982 antibody; STHAG7 antibody
Similar products	LRP6, Low-density lipoprotein receptor-related protein 6 (LRP-6)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	LRP6
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	ADCAD2 antibody; C030016K15Rik antibody; Cd antibody; FLJ90062 antibody; FLJ90421 antibody; LDL receptor related protein 6 antibody; Low density lipoprotein receptor related protein 6 antibody; Low-density lipoprotein receptor-related protein 6 antibody; LRP-6 antibody; LRP6 antibody; LRP6_HUMAN antibody; OTTHUMP00000238979 antibody; OTTHUMP00000238980 antibody; OTTHUMP00000238982 antibody; STHAG7 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Low-density lipoprotein receptor-related protein 6 protein (20-150AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Antigen Species	Human
Antigen	Recombinant Human Low-density lipoprotein receptor-related protein 6 protein (20-150AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 8/14/2025

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