Rabbit anti-human BBC3 polyclonal antibody

Bcl-2-binding component 3

Synthetic peptide of human BBC3

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification