Rabbit anti-human SIGLEC8 polyclonal antibody

sialic acid binding Ig-like lectin 8

Synthetic peptide of human SIGLEC8

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification