Rabbit anti-human NCOR1 polyclonal antibody

nuclear receptor corepressor 1

Synthetic peptide of human NCOR1

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification