Rabbit anti-human LRP5 polyclonal antibody

low density lipoprotein receptor-related protein 5

Synthetic peptide of human LRP5

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification