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SGO1 Antibody

ArtNr CSB-PA688764LA01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias hSgo 1 antibody; hSgo1 antibody; NY BR 85 antibody; Serologically defined breast cancer antigen NY BR 85 antibody; Serologically defined breast cancer antigen NY-BR-85 antibody; SGO 1 antibody; SGO antibody; SGO L1 antibody; SGO1 antibody; SGOL 1 antibody; SGOL1 antibody; SGOL1_HUMAN antibody; Shugoshin 1AB protein antibody; Shugoshin 1CD protein antibody; Shugoshin 1EFprotein antibody; Shugoshin 1GH protein antibody; Shugoshin 1KL protein antibody; Shugoshin like 1 (S. pombe) antibody; Shugoshin like 1 antibody; Shugoshin-like 1 antibody
Similar products SGOL1, SGO1, Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1)
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
SGO1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
hSgo 1 antibody; hSgo1 antibody; NY BR 85 antibody; Serologically defined breast cancer antigen NY BR 85 antibody; Serologically defined breast cancer antigen NY-BR-85 antibody; SGO 1 antibody; SGO antibody; SGO L1 antibody; SGO1 antibody; SGOL 1 antibody; SGOL1 antibody; SGOL1_HUMAN antibody; Shugoshin 1AB protein antibody; Shugoshin 1CD protein antibody; Shugoshin 1EFprotein antibody; Shugoshin 1GH protein antibody; Shugoshin 1KL protein antibody; Shugoshin like 1 (S. pombe) antibody; Shugoshin like 1 antibody; Shugoshin-like 1 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Shugoshin 1 protein (260-439AA)
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:5000
IF:1:50-1:200
Background
Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling
Antigen Species
Human
Antigen
Recombinant Human Shugoshin 1 protein (260-439AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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