Vergleich

Recombinant Human Somatotropin protein(GH1) (Active)

ArtNr CSB-AP000011HU-10
Hersteller Cusabio
Menge 10 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 250 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Konjugat/Tag Tag Free
Purity >98% as determined by SDS-PAGE and HPLC.
Sequence FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FE EAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNR EETQQK SNLELLRISL LLIQSWLEPV QFLRSV FANS LVYGASDSNV YDLLKDLEEG IQTLMGRL ED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F
Protein Familie Somatotropin/prolactin family
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Growth hormone,GH-N,Growth hormone 1,Pituitary growth hormone,
Lieferbar
Manufacturer - Category
Hormone / Hormone
Molecular Weight
22.0 kDa
Buffer
0.2 um filtered PBS, pH 7.4 , lyophilized
General Research Areas
Signal Transduction
Relevance
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Expression Region
27-127aa
Function
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Subcellular Location
Secreted
Involvement in disease
Growth hormone deficiency, isolated, 1A (IGHD1A); Growth hormone deficiency, isolated, 1B (IGHD1B); Kowarski syndrome (KWKS); Growth hormone deficiency, isolated, 2 (IGHD2)
Pathway
Jak-STATsignalingpathway
Gene Names
GH1
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Biological activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat Nb2-11 lymphoma cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
Manufacturer - Format
Lyophilized powder
Uniprot Entry Name
SOMA_HUMAN
Protein Description
Full Length of Mature Protein
PubMed ID
386281; 377496; 6269091; 7169009; 2744760; 18473352; 16625196; 10931946; 15489334; 3912261; 5810834; 5144027; 4675454; 5279046; 5279528; 7462247; 7356479; 7028740; 8364549; 14997482; 10393484; 16807684; 3447173; 1549776; 7984244; 8943276; 8552145; 9152628; 9276733; 10391209; 11502836; 12655557; 15001589; 15713716; 17519310

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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