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Recombinant Mouse Heat-stable enterotoxin receptor(Gucy2c),partial

ArtNr CSB-BP664972MO-1
Hersteller Cusabio
Menge 1 mg
Quantity options 1 mg 10 ug 100 ug 20 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Konjugat/Tag Myc, HIS
Purity Greater than 85% as determined by SDS-PAGE.
Sequence VFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNL REAVEEGLDIVRKRLREADLNVTVNATFIYSDGLI HKSGDCRSSTCEGLDLLREITRDHKMGCALMGPSC TYSTFQMYLDTELNYPMISAGSYGLSCDYKETLTR ILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYK NGSEPEDCFWYLNALEAGVSYFSEVLNFKDVLRRS EQFQEILTGHNRKSNVIVMCGTPESFYDVKGDLQV AED
Protein Familie Adenylyl cyclase class-4/guanylyl cyclase family
Citations "Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor."
Carrithers S.L., Ott C.E., Hill M.J., Johnson B.R., Cai W., Chang J.J., Shah R.G., Sun C., Mann E.A., Fonteles M.C., Forte L.R., Jackson B.A., Giannella R.A., Greenberg R.N.
Kidney Int. 65:40-53(2004)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Guanylyl cyclase C (GC-C) (Intestinal guanylate cyclase) (Guc2c)
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 10xHis-tagged and C-terminal Myc-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
51.1 kDa
Buffer
Tris-based buffer, 50% glycerol
General Research Areas
Microbiology
Relevance
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.
Expression Region
20-433aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin (By similarity).
Subcellular Location
Cell membrane, Single-pass type I membrane protein, Endoplasmic reticulum membrane, Single-pass type I membrane protein
Gene Names
Gucy2c
Sequence Info
Extracellular Domain
Organism
Mus musculus (Mouse)
Manufacturer - Format
Liquid or Lyophilized powder

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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