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Recombinant Human B-cell scaffold protein with ankyrin repeats(BANK1)

ArtNr CSB-YP836722HU-10
Hersteller Cusabio
Menge 10 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host Yeast
Konjugat/Tag HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MLPAAPGKGLGSPDPAPCGPAPPGNTKDIIMIYEE DAEEWALYLTEVFLHVVKREAILLYRLENFSFRHL ELLNLTSYKCKLLILSNSLLRDLTPKKCQFLEKIL HSPKSVVTLLCGVKSSDQLYELLNISQSRWEISTE QEPEDYISVIQSIIFKDSEDYFEVNIPTDLRAKHS GEISERKEIEELSEASRNTIPLAVVLPTEIPCENP GEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWN KKV
Citations BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor.Yokoyama K., Su I., Tezuka T., Yasuda T., Mikoshiba K., Tarakhovsky A., Yamamoto T.EMBO J. 21:83-92(2002)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 6xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
91.3 kDa
General Research Areas
Immunology
Relevance
Involved in B-cell receptor (BCR)-induced Ca2+ mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Expression Region
1-785aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Tissue Specificity
Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations.
Involvement in disease
Systemic lupus erythematosus (SLE)
Gene Names
BANK1
Sequence Info
Full Length
Organism
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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