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Recombinant Human B-cell scaffold protein with ankyrin repeats(BANK1)

Recombinant Human B-cell scaffold protein with ankyrin repeats(BANK1)

ArtNr	CSB-YP836722HU-100
Hersteller	Cusabio
Menge	100 ug
Quantity options	1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	other
Host	Yeast
Konjugat/Tag	HIS
Purity	Greater than 90% as determined by SDS-PAGE.
Sequence	MLPAAPGKGLGSPDPAPCGPAPPGNTKDIIMIYEE DAEEWALYLTEVFLHVVKREAILLYRLENFSFRHL ELLNLTSYKCKLLILSNSLLRDLTPKKCQFLEKIL HSPKSVVTLLCGVKSSDQLYELLNISQSRWEISTE QEPEDYISVIQSIIFKDSEDYFEVNIPTDLRAKHS GEISERKEIEELSEASRNTIPLAVVLPTEIPCENP GEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWN KKV
Citations	BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor.Yokoyama K., Su I., Tezuka T., Yasuda T., Mikoshiba K., Tarakhovsky A., Yamamoto T.EMBO J. 21:83-92(2002)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Lieferbar
Manufacturer - Conjugate / Tag	N-terminal 6xHis-tagged
Storage Conditions	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight	91.3 kDa
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
General Research Areas	Immunology
Relevance	Involved in B-cell receptor (BCR)-induced Ca2+ mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Expression Region	1-785aa
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Tissue Specificity	Expressed in B-cell but not T-cell or myeloid cell lines. Highest expression in CD19(+) B-cells, with very low expression in other cell populations.
Involvement in disease	Systemic lupus erythematosus (SLE)
Gene Names	BANK1
Sequence Info	Full Length
Organism	Homo sapiens (Human)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-YP836722HU-100-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 100 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 6 Tage sparen

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