Vergleich

CPSF4 Polyclonal Antibody

ArtNr E-AB-14891-200
Hersteller Elabscience
Menge 200 uL
Quantity options 120 uL 20 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cleavage and polyadenylation specific factor 4, 30kDa, Cleavage and polyadenylation specificity factor 30 kDa subunit, Cleavage and polyadenylation specificity factor subunit 4, cleavage polyadenylation specificity factor, 30kD, CPSF 30 kDa subunit, CPSF30, Cpsf4, CPSF4, NAR, Neb-1, NEB1, No arches homolog, no arches like zinc finger protein, NS1 effector domain binding protein 1, NS1 effector domain-binding protein 1, OTTHUMP00000206235, OTTHUMP00000206237, OTTHUMP00000206239
Similar products CPSF4, Cpsf4, CPSF30, NAR, NEB1, 30kD, 30kDa, Cleavage and polyadenylation specificity factor subunit 4, Cleavage and polyadenylation specificity factor 30 kDa subunit, CPSF 30 kDa subunit, NS1 effector domain-binding protein 1, Neb-1, No arches homolog, cleavage and polyadenylation specific factor 4, cleavage polyadenylation specificity factor, no arches like zinc finger protein, NS1 effector domain binding protein 1, OTTHUMP00000206235, OTTHUMP00000206237, OTTHUMP00000206239
Versandbedingung Gekühlt
Gefahren-Info Comply with cargo safety certificate
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
CPSF4
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30kDa
Research Areas
Epigenetics and Nuclear Signaling, Microbiology
Background
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Concentration
0.4 mg/mL
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Recommended Dilution
WB 1:500-1:2000
Santa Cruz #
sc-79418, sc-79417, sc-133480
Abbreviation
CPSF4
Clonality
Polyclonal
Immunogen
Recombinant protein of human CPSF4
Category ID III
Polyclonal Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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