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Phospho-FGFR4 (Tyr642) Polyclonal Antibody

ArtNr E-AB-21090-200
Hersteller Elabscience
Menge 200 uL
Quantity options 120 uL 20 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD 334, CD334, CD334 antigen, fc13h 10, fc13h10, Fgfr 4, FGFR-4, Fgfr4, FGFR4, Fibroblast growth factor receptor 4, Hydroxyaryl protein kinase, JTK 2, JTK2, MGC20292, Protein tyrosine kinase, TKF, Tyrosine kinase related to fibroblast growth factor receptor, Tyrosylprotein kinase
Similar products FGFR4, JTK2, TKF, Fibroblast growth factor receptor 4, CD334, MGC20292, Hydroxyaryl protein kinase, Protein tyrosine kinase, Tyrosylprotein kinase, FGFR-4, CD334 antigen, CD 334, fc13h 10, fc13h10, Fgfr 4, Fgfr4, JTK 2, Tyrosine kinase related to fibroblast growth factor receptor
Versandbedingung Gekühlt
Gefahren-Info Comply with cargo safety certificate
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
FGFR-4 (phospho Tyr642)
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
88kDa
Observed Molecular Weight
90kDa
Research Areas
Cancer, Cell Biology, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers
Background
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
Concentration
1 mg/mL
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Recommended Dilution
WB 1:500-1:2000
Abbreviation
FGFR-4 (phospho Tyr642)
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642
Category ID III
Acetyl/Phospho/Methyl Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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