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Phospho-FGFR4 (Tyr642) Polyclonal Antibody

Phospho-FGFR4 (Tyr642) Polyclonal Antibody

Item no.	E-AB-21090-200
Manufacturer	Elabscience
Amount	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Western Blot ELISA Primary Antibodies Astrocytoma By Organ Colorectal Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD 334, CD334, CD334 antigen, fc13h 10, fc13h10, Fgfr 4, FGFR-4, Fgfr4, FGFR4, Fibroblast growth factor receptor 4, Hydroxyaryl protein kinase, JTK 2, JTK2, MGC20292, Protein tyrosine kinase, TKF, Tyrosine kinase related to fibroblast growth factor receptor, Tyrosylprotein kinase
Similar products	FGFR4, JTK2, TKF, Fibroblast growth factor receptor 4, CD334, MGC20292, Hydroxyaryl protein kinase, Protein tyrosine kinase, Tyrosylprotein kinase, FGFR-4, CD334 antigen, CD 334, fc13h 10, fc13h10, Fgfr 4, Fgfr4, JTK 2, Tyrosine kinase related to fibroblast growth factor receptor
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FGFR-4 (phospho Tyr642)
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	88kDa
Observed Molecular Weight	90kDa
Research Areas	Cancer, Cell Biology, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers
Background	The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000
Abbreviation	FGFR-4 (phospho Tyr642)
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642
Category ID III	Acetyl/Phospho/Methyl Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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