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Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

ArtNr	ELS-PKSM040735-100ug
Hersteller	Elabscience
Menge	100 ug
Quantity options	100 ug 50 ug
Kategorie	Oncology By Cell Type Peptides & Proteins Recombinant Proteins
Typ	Proteins
Format	Lyophilized Powder
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Konjugat/Tag	HIS, Fc
Purity	> 97 % as determined by reducing SDS-PAGE.
Sequence	Tyr 22-Thr 212
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI503787, HAVcr-1, Hepatitis A virus cellular receptor 1 homolog, KIM-1, Kidney injury molecule 1, T cell membrane protein 1, TIM-1, Timd1
Similar products	TIM-1, Kidney injury molecule 1, Hepatitis A virus cellular receptor 1 homolog, HAVcr-1, KIM-1, T cell membrane protein 1, Timd1, AI503787
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His-Fc
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	49.0 kDa
Observed Molecular Weight	80-85 kDa
Background	HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â … integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile 20mM Tris-Citrate, 150mM NaCl, pH 6.5 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	A DNA sequence encoding the extracellular domain of mouse HAVCR1 isoform b (NP_001160104.1) (Tyr 22-Thr 212) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ELS-PKSM040735-100ug-datasheet.pdf

ELS-PKSM040735-100ug-safety-datasheet.pdf