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Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

Recombinant Mouse TIM1/HAVCR1 Protein (His & Fc Tag)

Item no.	ELS-PKSM040735-100ug
Manufacturer	Elabscience
Amount	100 ug
Quantity options	100 ug 50 ug
Category	Oncology By Cell Type Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Lyophilized Powder
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS, Fc
Purity	> 97 % as determined by reducing SDS-PAGE.
Sequence	Tyr 22-Thr 212
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI503787, HAVcr-1, Hepatitis A virus cellular receptor 1 homolog, KIM-1, Kidney injury molecule 1, T cell membrane protein 1, TIM-1, Timd1
Similar products	TIM-1, Kidney injury molecule 1, Hepatitis A virus cellular receptor 1 homolog, HAVcr-1, KIM-1, T cell membrane protein 1, Timd1, AI503787
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His-Fc
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	49.0 kDa
Observed Molecular Weight	80-85 kDa
Background	HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â … integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile 20mM Tris-Citrate, 150mM NaCl, pH 6.5 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	A DNA sequence encoding the extracellular domain of mouse HAVCR1 isoform b (NP_001160104.1) (Tyr 22-Thr 212) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM040735-100ug-datasheet.pdf

ELS-PKSM040735-100ug-safety-datasheet.pdf