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Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

ArtNr	ELS-PKSM041035-50ug
Hersteller	Elabscience
Menge	50 ug
Quantity options	10 ug 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins
Format	Liquid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Konjugat/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Gly19-Ser247
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CCP1, CTLA-1, Ctla-1, Ctla1, Cytotoxic cell protease 1, Fragmentin-2, Granzyme B(G,H), Gzmb
Similar products	CCP1, Gzmb, CTLA-1, Fragmentin-2, Granzyme B(G, H), Cytotoxic cell protease 1, Ctla-1, Ctla1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight	26.5 kDa
Observed Molecular Weight	35 kDa
Background	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Abbreviation	Granzyme B; GZMB
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Not Applicable
Formulation	Supplied as a 0.2 um filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ug

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Lieferung vsl. bis 05.06.2025

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