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TGFBR2/TGF-beta receptor type-2

TGFBR2/TGF-beta receptor type-2

ArtNr	E21-C10
Hersteller	Enogene
Menge	10 ug
Kategorie	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Glioma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma By Organ Colorectal Cancer
Typ	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	Human
Purity	Greater than 95% as determined by reducing SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TGF-beta receptor type-2,TGF-beta type II receptor,TGFBR2,Transforming growth factor-beta receptor type II
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Host	Human cells
Shipping Temperature	The product is shipped at ambient temperature. Ambient
Storage Conditions	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background	TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.
Description	Recombinant Human Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus.
Endotoxin	Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation Description	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2.
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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E21-C10-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 26.02.2026

Express-Lieferung: 16 Tage sparen

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