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TGFBR2/TGF-beta receptor type-2

TGFBR2/TGF-beta receptor type-2

Item no.	E21-C10
Manufacturer	Enogene
Amount	10 ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Glioma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma By Organ Colorectal Cancer
Type	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	Human
Purity	Greater than 95% as determined by reducing SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TGF-beta receptor type-2,TGF-beta type II receptor,TGFBR2,Transforming growth factor-beta receptor type II
Shipping Condition	Room temperature
Available
Manufacturer - Host	Human cells
Shipping Temperature	The product is shipped at ambient temperature. Ambient
Storage Conditions	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background	TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.
Description	Recombinant Human Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus.
Endotoxin	Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation Description	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2.
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 2/26/2026

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