Human FGF-4 Protein, His Tag

Protein

RT

19.8 kDa

Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.

FGF-4

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.8 kDa. The protein migrates as 23-24 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

MOPS, Na2SO4, Arginine

trehalose