beta-Amyloid (1-40)

Hersteller GenScript
Kategorie
Typ Peptides
Specific against other
Menge 1.0mg 
ArtNr RP20528-1
Eclass 6.1 34160400
Eclass 9.0 32160409
Lieferbar
Sequence (one-letter code)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Sequence (three-letter code)
{ASP}{ALA}{GLU}{PHE}{ARG}{HIS}{ASP}{SER}{GLY}{TYR}{GLU}{VAL}{HIS}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}{ALA}{GLU}{ASP}{VAL}{GLY}{SER}{ASN}{LYS}{GLY}{ALA}{ILE}{ILE}{GLY}{LEU}{MET}{VAL}{GLY}{GLY}{VAL}{VAL}
Description
Beta-amyloid peptide (beta-APP) is a 40-residue peptide implicated in the pathogenesis of Alzheimer’s disease (AD) and aged Down's Syndrome, which is promoted by the acquisition of an additional copy of chromosome 21. The peptide is a proteolytic product of the much larger amyloid precursor protein (APP) encoded by a gene on chromosome 21. The peptide comprises a large extracellular N-terminal domain and a short hydrophobic membrane-spanning domain, followed by a short C-terminal region. Beta-APP both precedes and forms part of the transmembrane region.
Solubility
Insoluble in water, may be dissolved in any buffer of pH >9.
Purity
> 95%
Storage
Store at -20C
Notes
This product is a chemically-modified beta-amyloid (1-40) precursor, which belongs to GenScript’s "click peptides".The "click peptides" are best described by the following key features: 1. Enhanced Stability—The O-acyl moiety within the click peptide is stable even under acidic pH. 2. Convenient and quick process—The "click peptides" can be easily converted to native peptide at pH 7.4 or above. 3. No by-product formation in the conversion process. 4. High Solubility in water compared to the native peptide. 5. Superior quality—After the "click", the aggregative property of the peptides is significantly minimized compared to its native format.
Menge: 1.0mg 
Lieferbar: Out of stock
Listenpreis: 290,81 €
Preis: 290,81 €
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