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Endostatin, Human

Endostatin, Human

Hersteller	GenScript
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules By Cell Type Carcinoma Hematology Leukemia Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma Cell Stainings ECM Cardiovascular Research Ischemia & Reperfusion Injury By Organ Lung Cancer Bladder Cancer
Typ	Proteins
Specific against	Human
Menge	100 ug
ArtNr	Z02533-100
Targets	VEGFA, FOXD3, FGF2
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Specificity	Determined by Endothelial Cell Tube Formation. The cells treated with 10μ, g/ml Endostatin showed significant anti-angiogenesis effect.
Description	Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
Endotoxin Level	Endotoxin level is less than 0.1 ng per ug (1EU/ug) of Endostatin.
Formulation	The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2.
Product Line	Others
Storage	The lyophilized Endostatin is stable for a few weeks at room temperature, but best stored at -20C. For the first use, reconstitute in water, aliquot and store at -20C to avoid multiple freeze-thaws.
Manufacturers Category	Proteins
Manufacturers Product Line	Other Proteins
Product Origin	USA

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Z02533-100-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 16.05.2024

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