Comparison

Endostatin, Human European Partner

Item no. Z02533-100
Manufacturer GenScript
Amount 100 ug
Quantity options 100 ug 20 ug
Category
Type Proteins
Specific against Human (Homo sapiens)
Purity Greater than 97% by SDS-PAGE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02533-Endostatin, Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.</td></tr><tr><th>Purity</th><td colspan="7"> Greater than 97% by SDS-PAGE</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Endotoxin level is less than 0.1 ng per ug (1EU/ug) of Endostatin.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Determined by Endothelial Cell Tube Formation. The cells treated with 10&
Similar products Endostatin
Shipping condition Cool pack
Available
Specificity Determined by Endothelial Cell Tube Formation. The cells treated with 10μ,g/ml Endostatin showed significant anti-angiogenesis effect.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Product Line
Other Proteins
Manufacturer - Specificity
Determined by Endothelial Cell Tube Formation. The cells treated with 10μ, g/ml Endostatin showed significant anti-angiogenesis effect.
Description
Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
Formulation
The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2.
Endotoxin Level
Endotoxin level is less than 0.1 ng per ug (1EU/ug) of Endostatin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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