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Angiostatin K1-3, Human Europäischer Partner

ArtNr Z02730-10
Hersteller GenScript
Menge 10 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against Human (Homo sapiens)
Purity >95% by SDS-PAGE and HPLC analyses.
Sequence VYLSECKTGN, GKNYRGTMSK, TKNGITCQKW, SSTSPHRPRF, SPATHPSEGL, EENYCRNPDN, DPQGPWCYTT, DPEKRYDYCD, ILECEEECMH, CSGENYDGKI, SKTMSGLECQ, AWDSQSPHAH, GYIPSKFPNK, NLKKNYCRNP, DRELRPWCFT, TDPNKRWELC, DIPRCTTPPP, SSGPTYQCLK, GTGENYRGNV, AVTVSGHTCQ, HWSAQTPHTH, NRT
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02730-Angiostatin_K1-3_Human, Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.</td></tr><tr><th>M.W.</th><td colspan="7"> Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5×105 IU/mg.</td></tr><tr><th>Storage</th><td colspan="7"> This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.</td></tr><tr><th>Reconstitution</th><td colspan="7"> We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.</td></tr><tr><th>Physical Appearance</th><td colspan="7"> Sterile Filtered White lyophilized (freeze-dried) powder.</td></tr><tr><th>Usage</th><td colspan="7"> This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.</td></tr><tr><th>Sequence</th><td colspan="7"> VYLSECKTGN, GKNYRGTMSK, TKNGITCQKW, SSTSPHRPRF, SPATHPSEGL, EENYCRNPDN, DPQGPWCYTT, DPEKRYDYCD, ILECEEECMH, CSGENYDGKI, SKTMSGLECQ, AWDSQSPHAH, GYIPSKFPNK, NLKKNYCRNP, DRELRPWCFT, TDPNKRWELC, DIPRCTTPPP, SSGPTYQCLK, GTGENYRGNV, AVTVSGHTCQ, HWSAQTPHTH, NRTPENFPCK, NLDENYCRNP, DGKRAPWCHT, TNSQVRWEYC, KIPSCDSSP</td></tr>
Similar products Angiostatin
Lieferbar
Specificity Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Storage Conditions
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Molecular Weight
Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
Product Line
Others
Manufacturer - Specificity
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg.
Description
Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.
Formulation
Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.
Endotoxin Level
Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method.
Usage
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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