Angiostatin K1-3, Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 10ug 
ArtNr Z02730-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Others
Description
Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.
M.W.
Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
Purity
>95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method.
Specific Activity
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg.
Storage
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Formulation
Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Usage
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Sequence
VYLSECKTGN, GKNYRGTMSK, TKNGITCQKW, SSTSPHRPRF, SPATHPSEGL, EENYCRNPDN, DPQGPWCYTT, DPEKRYDYCD, ILECEEECMH, CSGENYDGKI, SKTMSGLECQ, AWDSQSPHAH, GYIPSKFPNK, NLKKNYCRNP, DRELRPWCFT, TDPNKRWELC, DIPRCTTPPP, SSGPTYQCLK, GTGENYRGNV, AVTVSGHTCQ, HWSAQTPHTH, NRTPENFPCK, NLDENYCRNP, DGKRAPWCHT, TNSQVRWEYC, KIPSCDSSP
Menge: 10ug 
Lieferbar: In stock
Listenpreis: 76,86 €
Preis: 76,86 €
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