ArtNr |
Z02730-10 |
Hersteller |
GenScript
|
Menge |
10 ug |
Quantity options |
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Specific against |
Human (Homo sapiens) |
Purity |
>95% by SDS-PAGE and HPLC analyses. |
Sequence |
VYLSECKTGN, GKNYRGTMSK, TKNGITCQKW, SSTSPHRPRF, SPATHPSEGL, EENYCRNPDN, DPQGPWCYTT, DPEKRYDYCD, ILECEEECMH, CSGENYDGKI, SKTMSGLECQ, AWDSQSPHAH, GYIPSKFPNK, NLKKNYCRNP, DRELRPWCFT, TDPNKRWELC, DIPRCTTPPP, SSGPTYQCLK, GTGENYRGNV, AVTVSGHTCQ, HWSAQTPHTH, NRT |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
protein/Z02730-Angiostatin_K1-3_Human, Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.</td></tr><tr><th>M.W.</th><td colspan="7"> Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5×105 IU/mg.</td></tr><tr><th>Storage</th><td colspan="7"> This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.</td></tr><tr><th>Reconstitution</th><td colspan="7"> We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.</td></tr><tr><th>Physical Appearance</th><td colspan="7"> Sterile Filtered White lyophilized (freeze-dried) powder.</td></tr><tr><th>Usage</th><td colspan="7"> This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.</td></tr><tr><th>Sequence</th><td colspan="7"> VYLSECKTGN, GKNYRGTMSK, TKNGITCQKW, SSTSPHRPRF, SPATHPSEGL, EENYCRNPDN, DPQGPWCYTT, DPEKRYDYCD, ILECEEECMH, CSGENYDGKI, SKTMSGLECQ, AWDSQSPHAH, GYIPSKFPNK, NLKKNYCRNP, DRELRPWCFT, TDPNKRWELC, DIPRCTTPPP, SSGPTYQCLK, GTGENYRGNV, AVTVSGHTCQ, HWSAQTPHTH, NRTPENFPCK, NLDENYCRNP, DGKRAPWCHT, TNSQVRWEYC, KIPSCDSSP</td></tr> |
Similar products |
Angiostatin |
Lieferbar |
|
Specificity |
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg. |
Manufacturer - Category |
Proteins |
Country of Origin |
USA |
Storage Conditions |
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids. |
Product Line |
Others |
Manufacturer - Specificity |
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg. |
Description |
Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli. |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions. |
Formulation |
Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol. |
Endotoxin Level |
Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method. |
Usage |
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.