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Angiostatin K1-3, Human

Angiostatin K1-3, Human

Manufacturer	GenScript
Category	Food Safety Proteins Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	10 ug
Item no.	Z02730-10
Targets	FOXD3
eClass 6.1	34160400
eClass 9.0	42020190
Available
Specificity	Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5x105 IU/mg.
Description	Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.
Endotoxin Level	Less than 0.2EU/ug of rHuAngiostatin as determined by LAL method.
Formulation	Lyophilized from a 0.2um filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.
M.W.	Approximately 30.0 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
Product Line	Others
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Manufacturers Category	Proteins
Manufacturers Product Line	Other Proteins
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 5/9/2024