Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) , Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 10ug 
ArtNr Z02983-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokine, Chemokines & Growth Factors
Description
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils. Human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), can induce human endothelial cells to migrate and proliferate. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.
M.W.
22-28 kDa, observed by non-reducing SDS-PAGE.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 5x106 units/mg.
Storage
Lyophilized recombinant, human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 1 week at 4C or up to 2 months at -20C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Sequence
Ala18-Glu144 (Accession # CAA26822).
Note
For research use only
Menge: 10ug 
Lieferbar: In stock
Listenpreis: 99,99 €
Preis: 99,99 €
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