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GM-CSF, Human(CHO-expressed) Europäischer Partner

ArtNr Z02983-50
Hersteller GenScript
Menge 50 ug
Quantity options 1 mg 10 ug 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Sequence Ala18-Glu144 (Accession # CAA26822).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02983_50-Granulocyte_Macrophage_Colony_Stimulating_Factor_GM_CSF_Human,Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes,monocytes/macrophages and eosinophils. Human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), can induce human endothelial cells to migrate and proliferate. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.</td></tr><tr><th>M.W.</th><td colspan="7"> 22-28 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 5×106 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ala18-Glu144 (Accession
Similar products Granulocyte
Versandbedingung Gekühlt
Lieferbar
Specificity ED50, 5x106 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
22-28 kDa, observed by non-reducing SDS-PAGE.
Product Line
Growth Factors
Manufacturer - Specificity
ED50, 5x106 units/mg.
Description
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils. Human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), can induce human endothelial cells to migrate and proliferate. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Notes
For research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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