Fibroblast Growth Factor-8 (FGF-8), Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 1.0mg 
ArtNr Z02989-1
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokines, Chemokines & Growth Factors
Description
Fibroblast Growth Factor-8 (FGF-8), is a heparin-binding growth factor of the FGF family. There are 4 known forms of FGF8 produced by alternative splicing: FGF8a, FGF-8b, FGF-8e and FGF-8f. The human and mouse FGF8b are identical of aa sequences. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8 is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin- releasing hormone (GnRH) neuronal system. Recombinant, human Fibroblast Growth Factor-8 (rhFGF-8), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 194 amino acids. A fully biologically active molecule, rhFGF-8 has a molecular mass of 22.5kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
M.W.
22.5kDa, observed by reducing SDS-PAGE.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 2.0x 105 units/mg.
Storage
Lyophilized recombinant, human Fibroblast Growth Factor-8 (rhFGF-8), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhFGF-8 should be stable up to 2 weeks at 4C or up to 3 months at -20C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Sequence
Gln23-Arg215 (accession number: P55075), expressed with an N-terminal Met.
Note
For research use only
Menge: 1.0mg 
Lieferbar: In stock
Listenpreis: 1.462,00 €
Preis: 1.462,00 €
lieferbar

Angebot anfordern

Technische Fragen zu diesem Produkt?


Salesmanager: Arne Pelz

Email: sales@hoelzel.de

Schließen