ArtNr |
Z02989-10 |
Hersteller |
GenScript
|
Menge |
10 ug |
Quantity options |
1 mg
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Specific against |
Human (Homo sapiens) |
Purity |
> 95% by SDS-PAGE and HPLC analyses. |
Sequence |
Gln23-Arg215 (accession number: P55075), expressed with an N-terminal Met. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
protein/Z02989_10-Fibroblast_Growth_Factor_8_FGF_8_Human,Fibroblast Growth Factor-8 (FGF-8), is a heparin-binding growth factor of the FGF family. There are 4 known forms of FGF8 produced by alternative splicing: FGF8a, FGF-8b, FGF-8e and FGF-8f. The human and mouse FGF8b are identical of aa sequences. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8 is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin- releasing hormone (GnRH) neuronal system. Recombinant, human Fibroblast Growth Factor-8 (rhFGF-8), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 194 amino acids. A fully biologically active molecule, rhFGF-8 has a molecular mass of 22.5kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 22.5kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2.0× 105 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Fibroblast Growth Factor-8 (rhFGF-8), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhFGF-8 should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Gln23-Arg215 (accession number: P55075), expressed with an N-terminal Met.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr> |
Similar products |
Fibroblast |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Specificity |
ED50, 2.0x 105 units/mg. |
Manufacturer - Category |
Proteins |
Country of Origin |
USA |
Shipping Temperature |
4°C |
Storage Conditions |
-80°C |
Molecular Weight |
22.5kDa, observed by reducing SDS-PAGE. |
Product Line |
Growth Factors |
Manufacturer - Specificity |
ED50, 2.0x 105 units/mg. |
Description |
Fibroblast Growth Factor-8 (FGF-8), is a heparin-binding growth factor of the FGF family. There are 4 known forms of FGF8 produced by alternative splicing: FGF8a, FGF-8b, FGF-8e and FGF-8f. The human and mouse FGF8b are identical of aa sequences. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8 is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin- releasing hormone (GnRH) neuronal system. Recombinant, human Fibroblast Growth Factor-8 (rhFGF-8), produced in, E. coli, is a single non-glycosylated polypeptide chain containing 194 amino acids. A fully biologically active molecule, rhFGF-8 has a molecular mass of 22.5kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript. |
Reconstitution |
Reconstituted in ddH2O at 100 ug/ml. |
Formulation |
Lyophilized after extensive dialysis against PBS. |
Endotoxin Level |
< 0.2 EU/ug, determined by LAL method. |
Notes |
For research use only |
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