NANOG-TAT, Human

ArtNr	Z03001-100
Hersteller	GenScript
Menge	100 ug
Quantity options	100 ug 20 ug
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins S100 Calcium Binding Protein B Markers
Typ	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% by SDS-PAGE and HPLC analyses.
Dry ice	Yes
Sequence	Met1-Val305(Lys82Asn)(accession number: Q9H9S0), expressed with a C-terminal TAT peptide.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z03001_100-NANOG_TAT_Human,NANOG, is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Recombinant, human NANOG-TAT (rhNANOG-TAT), produced in, E. coli, is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 36.2 kDa, analyzed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7">< 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Storage</th><td colspan="7"> Recombinant, human NANOG-TAT (rhNANOG-TAT), remains stable up to 1-2 weeks at 4C from date of receipt. For long term storage, aliquot and store at -20C or -80C. Avoid repeated freezing and thawing cycles.</td></tr><tr><th>Formulation</th><td colspan="7"> Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.</td></tr><tr><th>Sequence</th><td colspan="7"> Met1-Val305(Lys82Asn)(accession number: Q9H9S0), expressed with a C-terminal TAT peptide.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products	NANOG-TAT
Lieferbar
Country of Origin	USA
Storage Conditions	Recombinant, human NANOG-TAT (rhNANOG-TAT), remains stable up to 1-2 weeks at 4C from date of receipt. For long term storage, aliquot and store at -20C or -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	36.2 kDa, analyzed by reducing SDS-PAGE.
Product Line	Cytokines, Chemokines & Growth Factors
Description	NANOG, is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Recombinant, human NANOG-TAT (rhNANOG-TAT), produced in, E. coli, is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Formulation	Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

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