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NANOG-TAT, Human

NANOG-TAT, Human

Item no.	Z03001-100
Manufacturer	GenScript
Amount	100 ug
Quantity options	100 ug 20 ug
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins S100 Calcium Binding Protein B Markers
Type	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% by SDS-PAGE and HPLC analyses.
Dry ice	Yes
Sequence	Met1-Val305(Lys82Asn)(accession number: Q9H9S0), expressed with a C-terminal TAT peptide.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z03001_100-NANOG_TAT_Human,NANOG, is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Recombinant, human NANOG-TAT (rhNANOG-TAT), produced in, E. coli, is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 36.2 kDa, analyzed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7">< 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Storage</th><td colspan="7"> Recombinant, human NANOG-TAT (rhNANOG-TAT), remains stable up to 1-2 weeks at 4C from date of receipt. For long term storage, aliquot and store at -20C or -80C. Avoid repeated freezing and thawing cycles.</td></tr><tr><th>Formulation</th><td colspan="7"> Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.</td></tr><tr><th>Sequence</th><td colspan="7"> Met1-Val305(Lys82Asn)(accession number: Q9H9S0), expressed with a C-terminal TAT peptide.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products	NANOG-TAT
Available
Country of Origin	USA
Storage Conditions	Recombinant, human NANOG-TAT (rhNANOG-TAT), remains stable up to 1-2 weeks at 4C from date of receipt. For long term storage, aliquot and store at -20C or -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	36.2 kDa, analyzed by reducing SDS-PAGE.
Product Line	Cytokines, Chemokines & Growth Factors
Description	NANOG, is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Recombinant, human NANOG-TAT (rhNANOG-TAT), produced in, E. coli, is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Formulation	Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Z03001-100-datasheet.pdf

Z03001-100-safety-datasheet.pdf