TNF Receptor Type I, Human

Hersteller GenScript
Typ Proteins
Specific against Human
Menge 10.0ug
ArtNr Z03104-10
eClass 6.1 34160400
eClass 9.0 42020190
TNF Receptor Type I, is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-kappaB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells, induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyer’s patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
Shipping Temperature
Menge: 10.0ug
Lieferbar: In stock
Listenpreis: 69,86 €
Preis: 69,86 €


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