RAT ANTI MOUSE ABCA1

GWB-F9CA70

IgG2a

Phosphate buffered saline pH7. 4

ABCA1 transfected HeLa cells.

cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport By similarity. Subunit structureInteracts with MEGF10. Ref. 5Subcellular locationMembrane; Multi-pass membrane protein Potential. Tissue specificityWidely expressed in adult tissues. Highest levels are found in pregnant uterus and uterus.

Multifunctional polypeptide with two homologous halves each containing an hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Post-translational modificationPhosphorylation on Ser-2054 regulates phospholipid efflux By similarity. Palmitoylation by DHHC8 is essential for membrane localization By similarity. Sequence similaritiesBelongs to the ABC transporter superfamily. ABCA family. Contains 2 ABC transporter domains. Sequence cautionThe sequence AAG39073. 1 differs from that shown. Reason: Erroneous initiation. The sequence CAA53530. 1 differs from that shown. Reason: Erroneous initiation. [1] \" Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF) a novel cytokine structurally related to IL-10 and inducible by IL-9. \" Dumoutier L. Louahed J. Renauld J. -C. J. Immunol. 164:1814-1819(2000) [PubMed: 10657629] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: AKR. [2] \" IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. \" Dumoutier L. Van Roost E. Colau D. Ameye G. Michaux L. Renauld J. -C. Genes Immun. 1:488-494(2000) [PubMed: 11197690] [Abstract]Cited for: NUCLEOTIDE SEQUENCE. Strain: 129. [3] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].