EAP30

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human EAP30.

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity. ELL contains a novel type of RNA polymerase II interaction domain that is capable of repreSummary: SNF8 VPS25 (MIM 610907) and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II) a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8 VPS25 and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al. 2005 [PubMed 15755741]; Kamura et al. 2001 [PubMed 11278625]). [supplied by OMIM]. Summary: SNF8 VPS25 (MIM 610907) and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II) a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8 VPS25 and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al. 2005 [PubMed 15755741]; Kamura et al. 2001 [PubMed 11278625]). [supplied by OMIM]. Schmidt. A. E. . et al. . (1999) Biol. Chem. 274 (31). 21981-21985.