RNF36

ArtNr	18-003-42586
Hersteller	GENWAY
Menge	0.05 mg
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody
Applikationen	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-8ABA8C
Similar products	18-003-42586
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Genway ID:	GWB-8ABA8C
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human RNF36.
ELISA Titre:	1:12500
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. RNF36 is specifically expressed in germ cells at round spermatid stages during spermatogenesis. The protein encoded by this gene contains an N-terminal RING finger motif. a B-box. and a C-terminal B-30. 2-like domain. When overexpressed in COS-7 and HEK-29
Function:	May play a role in apoptosis (By similarity).
Subunit:	Interacts with PML (By similarity).
Subcellular Location:	Nucleus speckle (By similarity).
Ptm:	Phosphorylated. Phosphorylation is necessary for nuclear localization (By similarity).
Similarity:	Belongs to the TRIM/RBCC family.
Similarity:	Contains 1 B30. 2/SPRY domain.
Similarity:	Contains 1 RING-type zinc finger. Summary: This protein is a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and when overexpressed induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. Shyu. H. W. . et al. . (2003) Exp. Cell Res. 287 (2). 301-313.

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Menge: 0.05 mg

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