ONECUT2 (one cut domain. family member 2)

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ONECUT2. Western Blot: Suggested dilution at 1. 25 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50. 000 - 100. 000 as second antibody. Protein Size: 485MW: 52kDa

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. ONECUT2 is a member of the transcription factors of the ONECUT class. whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted. the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.

Nucleus.

Contains 1 CUT DNA-binding domain.