GABRQ (gamma-aminobutyric acid (GABA) receptor. theta)

GWB-AA4BC4

1:12500

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor. theta subunit. GABRQ gene is mapped to chromosome

Generally pentameric. This subunit coassembles with alpha-2 beta-1 and gamma-1.

Belongs to the ligand-gated ionic channel (TC 1. A. 9) family [view classification]. Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This protein is GABA A receptor theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This protein location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). Sinkkonen. S. T. . et al. . (2000) J. Neurosci. 20 (10). 3588-3595.