Vergleich

YWHAB

ArtNr 18-003-43288
Hersteller GENWAY
Menge 0.05 mg
Kategorie
Typ Antibody
Applikationen WB
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-41E011
Similar products 18-003-43288
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Genway ID:
GWB-41E011
Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human YWHAB.
ELISA Titre:
1:62500
Note:
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. YWHAB belongs to the 14-3-3 family. members of which mediate signal transduction by binding to phosphoserine-containing proteins. YWHAB has been shown to interact with RAF1 and CDC25 phosphatases. suggesting that it may play a role in linking mitogenic si
Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Subunit:
Homodimer. Interacts with SSH1 and TORC2/CRTC2.
Subcellular Location:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Ptm:
Isoform alpha differs from isoform beta in being phosphorylated (By similarity).
Ptm:
Isoform Short contains a N-acetylmethionine at position 1 (By similarity).
Similarity:
Belongs to the 14-3-3 family. Summary: This protein is a protein belonging to the 14-3-3 family of proteins members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants which encode the same protein have been identified for this gene. Middleton. F. A. . et al. . (2005) Neuropsychopharmacology 30 (5). 974-983.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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