CCR7

ArtNr	18-272-196970
Hersteller	GENWAY
Menge	0.05 mg
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody
Applikationen	WB, IHC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-EA1DA7
Similar products	18-272-196970
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Genway ID:	GWB-EA1DA7
Isotype:	IgG
Immunogen:	Synthetic peptide: DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of Mouse CCR7.
Antigen Species:	Mouse
Specificity:	Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region. The antibody has been tested in an academic lab on cells transfected with CCR7 receptor we do not have information regarding its use against endogenous protein.
Positive Control:	Mouse spleen
Target:	CCR7
Localization:	Integral membrane protein.
Concentration:	1 mg/ml Storage
Buffer:	PBS 1mg/ml BSA 0. 1% sodium azide pH7. 2
Application Note:	ELISA: Use at a dilution of 1/100 000. IHC-P: Use at a dilution of 1/250. WB: Use at a dilution of 1/1000. The antibody has been tested in an academic lab on cells transfected with CCR7 receptor we do not have information regarding its use against endogenous protein. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Integral membrane protein. Receptors for the C - C chemokine family include CCR 1 CCR 2A CCR 3 CCR 4 CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
Function:	Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Subcellular Location:	Cell membrane; Multi-pass membrane protein.
Tissue Specificity:	Expressed in various lymphoid tissues and activated B- and T-lymphocytes strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Induction:	By EBV.
Similarity:	Belongs to the G-protein coupled receptor 1 family [view classification].

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Menge: 0.05 mg

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