CCR9

GWB-79B78E

Synthetic peptide: IPGMFDDFSYDSTASTDDYMNLNFSSFF corresponding to amino acids 10-37 of Mouse CCR9.

Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.

CCR9

2 mg/ml Storage

ELISA: Use at a dilution of 1/100000. FACS: Use at a dilution of 1/200. ICC: Use at a dilution of 1/500. IHC-P: Use at a dilution of 1/250. WB: Use at a dilution of 1/1000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

Cell membrane; Multi-pass membrane protein.

EC50 of SCYA25/TECK for isoform 1 is lower than for isoform 2.