Transferrin

ArtNr	18-272-198392
Hersteller	GENWAY
Menge	1 mg
Kategorie	Neuroscience Targets for Rodent Neurosciences Antibodies Primary Antibodies
Typ	Antibody
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-BA22E7
Similar products	18-272-198392
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Genway ID:	GWB-BA22E7
Immunogen:	Goats were immunized with highly purified rabbit transferrin in CFA. The antiserum was suitably solid phase absorbed to make it transferrin specific and the anti transferrin immunoaffinity purified
Antigen Species:	Rabbit
Target:	Transferrin
Concentration:	1 mg/ml Storage
Buffer:	PBS pH 7. 2 0. 1% sodium azide
Function:	Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Subunit:	Monomer.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed by the liver and secreted in plasma.
Polymorphism:	Different polymorphic variants of transferrin are known. The sequence shown is the predominant electrophoretic variant (C1 or TF*C1).
Disease:	Defects in TF are the cause of atransferrinemia [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
Miscellaneous:	The peptidase S60 domains do not have protease function as the catalytic residues are missing.
Similarity:	Belongs to the transferrin family.
Similarity:	Contains 2 peptidase S60 domains [view classification].

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Menge: 1 mg

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