Calpain 1 (small subunit)

GWB-723173

A synthetic peptide corresponding to residues in human Calpain 1 (small subunit) was used as an immunogen.

WB: 1:1000 - 2000IHC: 1:100 - 250ICC: 1:100 - 250FC: 1:100. Calcium-dependent cysteine proteinases or calpains are widely distributed in mammalian cells. There are 2 distinct molecular forms calpains 1 and 2 which differ in the quantity of calcium required. Both calpains 1 and 2 are heterodimeric; each is composed of 1 heavy (about 80 kD) CAPN1 and CAPN2 respectively and 1 shared light (about 30 kD) subunit CAPNS1. The heavy subunit has a catalytic function and the light subunit is regulatory. 1. Online Mendelian Inheritance in Man (OMIM) John Hopkins University Calpain small subunit 1; CAPNS1 (114170)2. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487