IL4 [BVD6-24G2] (PE)

BVD6-24G2

Recombinant full length protein (Mouse).

This product recognises murine IL4.

Secreted

0. 1 mg/ml

0. 09% Sodium Azide; Constituents: 0. 5% BSA PBS. pH 7. 2

Secreted The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13 which may contribute to many overlapping functions of this cytokine and IL13. STAT6 a signal transducer and activator of transcription has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene IL3 IL5 IL13 and CSF2 form a cytokine gene cluster on chromosome 5q with this gene particularly close to IL13. This gene IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Secreted.