IgG2b [LO-DNP-11] (FITC)

LO-DNP-11

Ovalbumin - Dinitrophenyl hapten (DNP)

IgG2b

0. 1 mg/ml Storage

For FACS and IHC-Fr: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. Myeloma: Spleen cells from an immunised Lou/c rat were fused with cells of the rat IR983F myeloma cell line. Immunoglobulin G (IgG) is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.