Vergleich

CD32

ArtNr 20-783-70080
Hersteller GENWAY
Menge 0.1 mg
Kategorie
Typ Antibody
Applikationen FC
Clon AT10
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-644160
Similar products 20-783-70080
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Genway ID:
GWB-644160
Specificity:
CD32. Clone AT10 blocks the binding of IgG to Fc gamma RII (4). NCBI
Gene ID:
2212
Isotype:
IgG1
Clone:
AT10
Product Form:
Purified igG conjugated to Biotin-liquidSynonyms: CD32 CD32 CD32 FCG2 FCG2 FCG2 FCGR2A1 IGFR2 IGFR2 IGFR2
Immunogen:
K562 cell line
Fusion Partner:
Spleen cells from immunised BALB/c mice were fused with cells of the NS1 myeloma cell line.
Specificity Note:
This product recognises the human CD32 antigen a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis activation of secretion cytotoxicity and immunomodulation. CD32 is expressed by B cells monocytes granulocytes and platelets. Clone AT10 blocks the binding of IgG to Fc gamma RII (4). is recommended for this purpose.
Preparation:
Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide 1% Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells or 100ul whole bloodSuggested
Dilution:
Flow Cytometry - Neat 1. Greenman. J. et al. (1991) Characterisation of a new monoclonal anti-Fc gamma RII antibody. AT10. and its incorporation into a bispecific F(ab\' )2 derivative for recruitment of cytotoxic effectors. 2. van den Herik-Oudijk. I. E. et al. (1994) Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes. 3. Lilliehook. I. et al. (1998) Expression of adhesion and Fc gamma - receptors on canine blood eosinophils and neutophils studied by anti-human monoclonal antibodies. 4. Larsson. M. et al. (1997) Human dendritic cells handling of binding. uptake and degradation of free and IgG - immune complexed dinitrophenylated human serum albumin in vitro.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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