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NQO1 Antibody (Center)

NQO1 Antibody (Center)

ArtNr	ABC-AP7350C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NQO1, DIA4, DTD, NMOR1, QR1, DT-diaphorase, NAD(P)H dehydrogenase [quinone] 1, Azoreductase, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1
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Primary Accession	P15559
Antigen Type	Synthetic Peptide
Application	IF, FC, WB
Bio Background	NQO1 is a member of the NAD(P)H dehydrogenase(quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
Bio References	Hubackova, M., Vaclavikova, R. Pharmacogenet. Genomics 19 (7), 505-512 (2009) Canova, C., Hashibe, M. Cancer Res. 69 (7), 2956-2965 (2009) Li, Y. and Jaiswal, A.K. J. Biol. Chem. 267 (21), 15097-15104 (1992)
Clonality	Polyclonal
Clone/Animal Names	RB19087
Gene ID	1728
Gene Name	NQO1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of NQO1 Antibody (Center)(Cat#AP7350c) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of NQO1 antibody (Center) (Cat.#AP7350c) in NCI-H460 cell line lysates (35ug/lane). NQO1 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	NQO1 antibody (Center) (Cat.#AP7350c) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	30868
Antigen Region	118-144
Antigen Source	HUMAN
Target/Specificity	This NQO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NQO1.
NCBI Accession	NP_000894.1; NP_001020604.1; NP_001020605.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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