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EGFR Antibody (S1070)

EGFR Antibody (S1070)

ArtNr	ABC-AP7628s
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
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Primary Accession	P00533
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Bio References	Zanardi, T.A., et al., J. Virol. 77(21):11685-11696 (2003). Krug, A.W., et al., J. Biol. Chem. 278(44):43060-43066 (2003). Huang, F., et al., J. Biol. Chem. 278(44):43411-43417 (2003). He, Y.Y., et al., J. Biol. Chem. 278(43):42457-42465 (2003). Hirsch, F.R., et al., J. Clin. Oncol. 21(20):3798-3807 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB12736
Gene ID	1956
Gene Name	EGFR (HGNC:3236)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-EGFR Antibody (S1070) (Cat.#AP7628s) in kidney heart tissue lysates (35ug/lane). EGFR(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of EGFR (arrow) in Hela cell lysates, either induced (Lane 1) or noninduced with EGF (Lane 2).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EGFR Antibody (S1070), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	134277
Antigen Region	1048-1077
Antigen Source	HUMAN
Target/Specificity	This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1048-1077 amino acids from human EGFR.
NCBI Accession	NP_005219.2; NP_958439.1; NP_958440.1; NP_958441.1

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Menge: 400 ul

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