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EGFR Antibody (S1070)

EGFR Antibody (S1070)

Item no.	ABC-AP7628s
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Available
Primary Accession	P00533
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Bio References	Zanardi, T.A., et al., J. Virol. 77(21):11685-11696 (2003). Krug, A.W., et al., J. Biol. Chem. 278(44):43060-43066 (2003). Huang, F., et al., J. Biol. Chem. 278(44):43411-43417 (2003). He, Y.Y., et al., J. Biol. Chem. 278(43):42457-42465 (2003). Hirsch, F.R., et al., J. Clin. Oncol. 21(20):3798-3807 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB12736
Gene ID	1956
Gene Name	EGFR (HGNC:3236)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-EGFR Antibody (S1070) (Cat.#AP7628s) in kidney heart tissue lysates (35ug/lane). EGFR(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of EGFR (arrow) in Hela cell lysates, either induced (Lane 1) or noninduced with EGF (Lane 2).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EGFR Antibody (S1070), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	134277
Antigen Region	1048-1077
Antigen Source	HUMAN
Target/Specificity	This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1048-1077 amino acids from human EGFR.
NCBI Accession	NP_005219.2; NP_958439.1; NP_958440.1; NP_958441.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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