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Biotinylated Human HLA-A*11:01&B2M&EBV (AVFDRKSDAK) Complex Protein (Monomer, MALS verified) Europäischer Partner

ArtNr HLE-H82E5-25ug
Hersteller ACROBiosystems
Menge 25 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Biotin, HIS, Avi
Purity 90%
Formula PBS, pH7.4
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-10xHis & C-Avi, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
36.0 kDa and 11.7 kDa
Manufacturer - Format
Powder
Description
Biotinylated Human HLA-A*11:01&B2M&EBV (AVFDRKSDAK) Complex Protein (HLE-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & AVFDRKSDAK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & AVFDRKSDAK).
Background
Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. The Human HLA-A*1101 EBV (AVFDRKSDAK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M and AVFDRKSDAK peptide of the EBV.
Molecule
HLA-A*1101 & B2M & EBV (AVFDRKSDAK)
Exp Region
Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & AVFDRKSDAK peptide
Characteristics
Biotinylated Human HLA-A*11:01&B2M&EBV (AVFDRKSDAK) Complex Protein is produced by co-expression of HLA and B2M loaded with EBV peptide.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 38-43 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 21.08.2025 

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